Hyaluronic Acid reinvents itself

Biotechnology and molecular fragmentation

Biotechnology means “any technological application that uses biological systems, living organisms or their derivatives, to create or modify products or processes for a specific use”.

Bacteria, yeasts or microalgae represent the basis for the development of innovative ingredients that are also useful for future developments thanks to their versatility and low environmental impact compared to other sources.

Among the known examples of biotechnological application there is bacterial fermentation with the production of highly pure metabolites; such as Hyaluronic Acid - (HA) - an effective and safe substance that today acquires a new appeal in the eyes of a consumer always looking for novelties, thanks to new experimental scientific data and clinical observations.

HA is a glycosaminoglycan, which constitutes a significant portion of the extracellular matrix in the human dermis, in which living cells and fibrous polymers (collagen and elastin) are immersed. Its degradation is a key factor in alterations in skin hydration, turgor and architecture.

In recent years it has been ascertained that keratinocytes, in the epidermal area, also produce HA and release it into the surrounding interstitial spaces where it reaches even higher concentrations than those of the dermis; but with a short permanence in this area.

Currently, fragmented HA of different molecular weights (MW) is widely used, since a synergistic effect occurs between molecules of different sizes which, when combined together, create optimal conditions for preventing and counteracting the skin aging process.

The choice of fragmented HA is therefore linked to the ability to replenish moisture in the skin and retain water for a prolonged period; the skin appears smoother and brighter. Constant hydration slows down the formation of wrinkles and improves fine or deep lines already developed, while increasing cell regeneration and stimulating collagen production.